RAMAN CHEMICAL IMAGING TECHNOLOGIES AND METHODS

Price:	Conferee: $315; Student: $50; Non-conferee: $415
Date:	Sunday, October 17, 8:00 am
Location:	Half day course, Morning Workshop
Instructors:	Ryan J. Priore and Matt Nelson, ChemImage

Chemical Imaging is a rapidly maturing discipline that involves the integration of digital imaging with molecular spectroscopy, relying on Raman, fluorescence, visible, NIR and IR absorption/reflectance techniques. It has evolved as a powerful approach for non-invasive characterization of chemical heterogeneity. Among these techniques, Raman Chemical Imaging is particularly suited for microspectroscopy and imaging due to the inherent selectivity and sensitivity of Raman spectroscopy. Two different imaging approaches, spatial and wavelength scanning, are used to acquire a hyperspectral data cube containing wavelength, intensity, x, y and z- spatial information. This course emphasizes wavelength scanning approaches to Raman Chemical Imaging which enable rapid image acquisition with diffraction-limited spatial resolution. In widefield Raman Chemical Imaging, thousands of Raman spectra are simultaneously collected from a field of view. The spectral data is used to generate chemically-specific images. Intricate image and spectral processing techniques may be applied to the chemical imaging data to produce various qualitative and/or quantitative parameters associated with the often complex sample matrix. This short course is designed as a comprehensive overview of theoretical and practical aspects of Raman Chemical Imaging and associated instrumentation. The special emphasis is placed on Raman Chemical Imaging applications in pharmaceutical and biothreat detection fields. This course will be useful to analytical, forensic, biomedical and materials chemists.

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