Comprehensive focus on understanding the fundamentals of the most widely used mass spectrometers and sample inlet technologies: how and where are they employed to the practitioners’ best advantage. The examples include how designing the separation and avoiding pitfalls of combining LC, GC and MS can increase analytical success. Discussion includes the latest technologies such as non-LC atmospheric ionization techniques DESI, DART, ASAP and MALDI imaging for tissues.

The course is designed for anyone in pharma, industry or environmental practice employing MS for small molecule investigations including design of experiment considerations (column chemistries, solvents and ionization methods), quantitative considerations, qualitative considerations (spectral interpretation) and identification of target compounds in complex matrices. In addition to course materials, references for further study and glossaries explaining commonly used terms, the take-home value of attending for students is gaining an overall view of current mass spectrometry practice and the opportunity to address individual questions.